Unforeseen In Animal Tests

Newspaper headlines 16 Nov 2011 to 24 Feb 2012

“Antipsychotics death risk charted in dementia patients”
BBC News. 24 February 2012.

“Alzheimer’s Drugs Harmful? The researcher who helped develop an Alzheimer’s treatment now in clinical trials warns that the compound may actually impair memory.”
The Scientist. 20 February 2012.

“HIV drug tenofovir increases risk of kidney damage”
SF Gate. 18 February 2012.

“Novartis to Add Warnings to Rasilez Blood-Pressure Drug”
Bloomberg. 17 February 2012.

“Cause of deaths unclear in Actelion drug trial”
Chicago Tribune. 14 February 2012.

“The MedWatch January 2012 Safety Labeling Changes posting includes 63 products with safety labeling changes to the following sections:
BOXED WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS and PATIENT PACKAGE
INSERT.”
FDA Medwatch. 13 February 2012.

“Appetite suppressant was probably responsible for 1300 deaths, study shows.”
BMJ 2012; 344 doi: 10.1136/bmj.e996 (Published 9 February 2012)

“Panel Nixes AML Indication for Dacogen.”
Medpage Today. 9 February 2012.

“New Antibiotic for Bladder Infection Disappoints in Trial.”
Healthday. 8 February 2012.

“Certain Cancer Drugs May Have Fatal Side Effects: Analysis.”
US News Health. 8 February 2012.

“FDA Issues Warning on Acid Reflux Drugs.”
Medpage Today. 8 February 2012.

“Bridport youngster in marrow transplant after cancer drug trial failure.”
Dorset Echo. 8 February 2012.

“Pfizer’s Breast-Cancer Drug Worsens Bone Loss in Older Women.”
Bloomberg. 7 February 2012.

“US Drug Watchdog Expands Their Initiative for Diabetics Who Used the
Diabetes Drug Actos and Then Developed Bladder Cancer with
Focus on Compensation & the Best Lawyers.”

PRWeb. 6 February 2012.

“Certain Cancer Drugs May Have Fatal Side Effects”
Healthday. 6 February 2012.

“Cancer-Deterring Drug Found to Harm Bones.”
New York Times. 6 February 2012.

“Type 1 Diabetes Treatment Disappoints in Trial. Vaccine-based
approach didn't affect insulin needs or other markers.”

Healthday. 1 February 2012.

“Heartburn Drugs May Raise Fracture Risk in Older Women”
Healthday. 31 January 2012.

“Diabetes drugs tied to pancreatic cancer risk”
Reuters. 31 January 2012.

“Infinity craters after lead drug flunks PhII cancer study.”
Fierce Biotech. 27 January 2012.

“Novartis’s Gilenya Pill Reviewed by EU, U.S. After 11 Deaths”
Bloomberg Business Week. 22 January 2012.

“AstraZeneca May Rethink Aversion to Big Deals After Setbacks”
Bloomberg Business Week. 22 January 2012.

“Thousands of women could be at risk from 'silent Thalidomide'. A drug
intended to prevent miscarriage is blamed for causing cancer in the daughters
– and possibly even granddaughters – of women who took it decades ago.”

Independent on Sunday. 22 January 2012.

“Bristol, AstraZeneca Diabetes Drug Fails to Win FDA Backing.”
Bloomberg Business Week. 19 January 2012.

“Merck to pay at least $21.8 million to settle Vioxx lawsuits in Canada”
Canadian Business. 19 January 2012.

“Bristol, AstraZeneca Diabetes Drug Fails to Win FDA Backing.”
Bloomberg Business Week. 19 January 2012.

“Pfizer, Medivation End Alzheimer Drug’s Work After Failure.”
Bloomberg Business Week. 19 January 2012.

“Roche Flu Drug’s Effectiveness Is Unproven, Researchers Say”
Bloomberg Business week. 19 January 2012.

“Melanoma Drug's Link to Other Skin Cancers Identified. New study suggests
ways around the risk for patients.”

HealthDay. 18 January 2012.

“Pfizer, Medivation End Drug Development Deal”
Sci-Tech Today. 18 January 2012.

“Big Pharma Routinely Suppresses Data from Clinical Trials—but FDA Approves
These Dangerous Drugs Anyway!”

ANH. 17 January 2012.

“Side effects and effectiveness of 'wonder-drug' Tamiflu under the microscope as Department of Health faces awkward questions over mass prescriptions”
Daily Mail, 17 January 2012

“Antidepressant Use Linked to Increased Pulmonary Hypertension Risk in Infants.”
New York Times. 13 January 2012.

“Seattle Genetics Lymphoma Drug Gets Boxed Warning on Brain Infection Risk.”
Bloomberg. 13 January 2012.

“Adcetris (brentuximab vedotin): Drug Safety Communication.”
FDA. 13 January 2012.

“The MedWatch December 2011 Safety Labeling Changes posting includes 40
products with safety labeling changes to the following sections: BOXED
WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE
REACTIONS and PATIENT PACKAGE INSERT.”

FDA Medwatch. 12 January 2012.

“Boehringer’s Pradaxa Increases Risk of Heart Attack, Study Shows.”
Bloomberg Business Week. 10 January 2012.

“Statins Tied to Lung Damage in Smokers.”
MedPageToday. 6 January 2012.

“Drug Falls Short In Cancer Study”
WSJ. 30 December 2011.

“Epidurals Linked to Paralysis Seen With $300 Billion Pain Market.”
Bloomberg. 28 December 2011.

“The growing downside of cholesterol drugs. 'The harms are really starting to catch up,' says researcher of widely prescribed statins.”
Vancouver Sun. 28 December 2011.

“Bristol-Myers Says Liver Cancer Drug Didn’t Meet Goals in Trial.”
Bloomberg Business Week. 23 December 2011.

“Bristol-Myers: Experimental liver cancer drug failed in late-stage study, other tests continue.”
Washington Post. 22 December 2011.

“FDA to probe Gilenya patient death”
Inpharm. 21 December 2011.

“Targeted drug side effects add to cancer costs.”
Reuters. 21 December 2011.

“Sanofi, Novartis, Astrazeneca get poor results from trial tests on key drugs.”
Washington Post. 20 December 2011.

“Genzyme phase 3 study fails to show superiority for MS drug.”
Pro Active Investor. 20 December 2011.

“Heart drug doubles risk for heart failure.”
All Voices. 20 December 2011.

“Targacept plunges on second drug study failure.”
CNBC. 20 December 2011.

“Gilenya (fingolimod): Drug Safety Communication - Safety Review of a Reported Death After The First Dose.”
FDA Medwatch. 20 December 2011.

“Three European companies douse hopes for new drugs.”
Reuters. 20 December 2011.

“Nausea drug may be linked with sudden cardiac death.”
Irish Times. 19 December 2011.

“Child Cancer Drugs May Cause Problems Later, Study.”
Medical Daily. 19 December 2011.

“Multaq, Heart Rhythm Drug, Linked With Heart Attack And Stroke Risks; FDA Adds Safety Warnings.”
Huffington Post. 19 December 2011.

“Multaq (dronedarone): Drug Safety Communication - Increased Risk of Death or Serious Cardiovascular Events.”
FDA Medwatch. 19 December 2011.

“Pediatric anticancer drugs, other drugs linked to heart disease.”
Food Consumer. 17 December 2011.

“Pfizer Settled About Half of Prempro Cases, Adds to Reserve.”
Bloomberg. 15 December 2011.

“BioSante's "female viagra" fails late-stage trials.”
Reuters. 14 December 2011.

“This includes 48 products with safety labeling changes to the following sections: BOXED WARNINGS, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, PATIENT PACKAGE INSERT, and MEDICATION GUIDE.”
MedWatch November 2011 Safety Labeling Changes posting. FDA Medwatch. 13 December 2011.

“Actelion pulls out of Trophos buy after ALS drug failure.”
Pharma Times. 14 December 2011.

“Selective Serotonin Reuptake Inhibitor (SSRI) Antidepressants: Drug Safety Communication- Use During Pregnancy and Potential Risk of Persistent Pulmonary Hypertension of the Newborn.
FDA Medwatch. 14 December 2011.

“Rare birth defects tied to mom's painkiller use.”
Chicago Tribune. 13 December 2011.

“Some depressed people do worse on drugs: study.”
Reuters. 12 December 2011.

“Scandal Over Mediator, a French Weight-Loss Drug, Prompts Calls for Wide Changes.”
New York Times. 11 December 2011.

“Glaxo's Tykerb Misses Goal In Breast Cancer Trial.”
WSJ. 9 December 2011.

“FDA advisers: revise popular birth control labels.”
Reuters. 8 November 2011.

“More Detail on Risk Urged for a Contraceptive Label.”
New York Times. 8 December 2011.

“More Detail on Risk Urged for a Contraceptive Label.”
New York Times. 8 December 2011.

“FDA staff worried about lung risk with Alexza drug.”
Reuters. 8 December 2011.

“EUROECHO: Cancer Drug Has Early Cardiac Effects.”
MedPageToday. 8 December 2011.

“Alexza’s Inhaled Antipsychotic May Pose Lung Risks, FDA Says.”
Bloomberg Business Week. 8 December 2011.

“Pradaxa (dabigatran etexilate mesylate): Drug Safety Communication - Safety Review of Post-Market Reports of Serious Bleeding Events.”
FDA Medwatch. 7 December 2011.

“FDA says Yaz and related birth control pills should carry more info about risk of blood clots.”
Washington Times. 7 December 2011.

“Pfizer’s Kidney Cancer Drug May Not Be Effective, FDA Staff Report Says.”
Bloomberg. 5 December 2011.

“After heart attacks, two types of drugs are commonly prescribed: antiplatelet treatment and selective serotonin reuptake inhibitors (SSRI) for depression. A retrospective analysis of patients discharged after acute myocardial infarction over 10 years found that compared with aspirin alone, the combined use of an SSRI and antiplatelet therapy resulted in a higher risk of bleeding.”
BMJ 2011; 343 doi: 10.1136/bmj.d7681 (Published 30 November 2011)

“GSK diabetes drug fails first of seven phase 3 clinical trials”
WRALtech. 16 November 2011.

 

From Dusk 'til Dawn
An Insider's View of the Growth of the Animal Liberation Movement

© Keith Mann
puppypincher@yahoo.co.uk